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Prof. Alessio Fasano (MD) is Director of EBRIS, Vice Chair of Basic, Translational, and Clinical Research and Division Chief of Paediatric Gastroenterology and Nutrition at the Mass General Hospital for Children in Boston. He also serves as the Director of the Mucosal Immunology and Biology Research Centre and Director of the Centre for Celiac Research at the same Institution. In recent years, Dr. Fasano’s research has focused on the pathophysiology and role of intercellular tight junctions and gut microbiome in the pathogenesis of autoimmune and inflammatory diseases, with special emphasis on celiac disease and type 1 diabetes. Dr. Fasano has published more than 280 peer-reviewed papers and has filed more than 160 patent applications, many of which have been granted. Dr. Fasano has been awarded several prizes for his translational science, including the 2012 Shwachman Award, the 2012 Magister Insignins Award, the 2013 Linus Pauling Award and the 2014 Paul Harris Fellow Award. Dr Fasano identified in 2000 for the first time a protein that modulates the permeability of tight junctions between cells of the wall of the digestive tract, zonulin, that revolutionized our ability to understand the gut and permeability and how this impacts a wide range of health conditions from cancer to autoimmune disease to inflammation and food sensitivities.
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